The 2025/26 Serie A season kicks off with a compelling match, as Lecce will travel to the iconic Luigi Ferraris, where they will take on Genoa on August 23rd, 2025. This fixture promises a lot. Thus, there are likely to be differing strategies and selection policies at work, as both sides have a chance to put their early-season marker down. Genoa are under new management with Patrick Vieira, and Lecce are managed by Eusebio Di Francesco (with plenty of experience). Given how important each fixture is within the campaign and the differing trajectories and aspirations of each side, we expect an engaging encounter. 

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This match isn't just going to set the tone for the season for both teams; it's also a chance for fans to see two managers navigate their transitional summers.

• Prediction of correct score: Genoa 3 - 1 Lecce 

Bookmakers are more favorable towards Genoa, particularly with their head-to-head historical track record against Lecce and good play under the leadership of Vieira. In terms of betting, this provides enticing options in various markets:

Patrick Vieira has created a new style of play since taking over from Alberto Gilardino last season. With his 4-2-3-1 formation, his team builds from the back, plays wide when attacking, and presses all over the pitch.

Leali (GK); Norton-Cuffy, Ostigard, Vasquez, Martin; Frendrup, Masini; Carboni, Stanciu, Gronbaek; Colombo.

Eusebio Di Francesco came back for his second stint looking to steady a Lecce side that just avoided relegation last season. However. His recent history does cause concern, with back-to-back relegations at Frosinone and Venezia.

Falcone (GK); Kouassi, Gabriel, Gaspar, Gallo; Coulibaly, Pierret, Helgason; Morente, Camarda, Sottil.

Most Recent H2Hs at Luigi Ferraris:

Genoa Strengths:

• Good record at home—They have been really dominant while playing at Luigi Ferraris.

• New players settling in well—Carboni and Stanciu have already scored.

• Compact midfield—Gronbaek and Frendrup work well together.

Lecce Weaknesses:

• Poor record on the road—They have not had a win over Genoa in Genoa since 1998.

• They've lost some important players—Krstovic and Baschirotto have left and taken away much of the spine of the team.

• They do not have a stable managerial situation—Di Francesco has been inconsistent in previous stints as manager.

Keep an eye on Lorenzo Colombo, the former Lecce striker who's now on loan at Genoa from AC Milan. He's definitely a player to watch! Colombo is known for scoring first in 8 of his 14 Serie A goals, and this would be a memorable match to score against his former club. He should play well in Vieira's attacking style of play.

Although Lecce are put in a tough spot and will fight hard, the odds, form, and history are all overwhelmingly in favor of Genoa. Vieira's team will want to kick off their season with a comprehensive win on home soil.

Genoa enter their opening match of the Serie A 2025/26 season against Lecce as clear favorites. With strategic stability, new signings having settled, and a good home record, the Rossoblu should be able to find a way to win on the opening day. Lecce, on the other hand, must overcome their historic challenges while dealing with absences in order to break the trend of a poor start.