The stakes are highest they ever were as the 2025 US Open women's singles draw enters the quarter-final stage. The competition has been whittled down to an extremely successful group of players, and every remaining player has reached a Grand Slam final within their playing career. Two of the most compelling storylines in women's tennis will be acted out at Arthur Ashe Stadium on September 2.

In one of the most anticipated rematches of their Wimbledon final, the dominant Iga Swiatek will face the back, Amanda Anisimova. In the later evening session, the dominant World No. 1 Aryna Sabalenka will face the shrewd and volatile Marketa Vondrousova. Both matches have huge implications for the world rankings and the ultimate title as well, so a day of high-pressure drama and brilliance in tennis is in store.

• Date: Wednesday, September 3rd, 2025

• Time: 5.10 PM (UTC)

• Venue: Arthur Ashe Stadium, Flushing Meadows, New York

• Competition: US Open Women's Singles Quarter-Final

Iga Swiatek has been in sensational form all season. The Wimbledon winner is calmly having her greatest-Grand Slam season on record with at least a semi-final appearance in all the majors in 2025. She has been ruthless at Flushing Meadows, losing only one set en route to the quarterfinals. Her demolition of Ekaterina Alexandrova in the fourth round was a demonstration of her merciless groundstrokes and strangling defense. The Pole is not just battling for a semi-final spot; a good show will also allow her to pass her rival, Aryna Sabalenka, and recapture the World No. 1 position.

Amanda Anisimova, meanwhile, has been on a redemptive path. Having got off to a tough beginning to the year, the American 24-year-old has played her finest tennis on home ground. Her quarter-final run is her career-best US Open performance, and she has seemed absolutely assured and commanding in her last couple of games. She dispatched Beatriz Haddad Maia in the fourth round with a commanding 6-0, 6-3 win. With her brash, aggressive play and added maturity, Anisimova believes she has the tools to compete with the top players in the world, and she'll be looking to prove it against a player who administered her painful defeat just a few months ago.

Head-to-head between these two players is dominated by a single result that is impossible to ignore. They met once in their careers, and that was in the 2025 Wimbledon Championships final.

While the statistics are gloomy, they do not tell the whole story. Anisimova's impressive run to the Wimbledon final included a victory over Aryna Sabalenka and showed that she has the talent to compete at the highest level.

The tactical battle will be a clash of raw power with defensive genius. Anisimova will attempt to control the points from behind the court, using her hot, flat groundstrokes to get Swiatek moving. She must be bold and control the rallies in order to have a chance. Swiatek, on the other hand, will rely on her trademark relentless pursuit of the court, excellent footwork, and hard-court-specialist serve that has developed into a significant tool. Her strategy will be to absorb Anisimova's power and then turn defense into offense, using her variety and spin to induce unforced errors.

• Date: Tuesday, September 2, 2025

• Time: 11.00 UTC

• Venue: Arthur Ashe Stadium, Flushing Meadows, New York

World No. 1 Aryna Sabalenka, the runaway favorite, has provided an exemplary beginning to her US Open title defense. She has moved into the quarterfinals without dropping a set, taking under six hours of court time. Her destroying fourth-round performance against Cristina Bucsa was a brutal masterclass in controlling dominance that showed she is peaking and in very strong pursuit of her fourth Grand Slam title. Sabalenka is a three-time Grand Slam winner and her major’s consistency has been phenomenal, reaching the quarterfinals in all her last 12 Grand Slam events.

Wimbledon champion and unseeded Marketa Vondrousova is the top contender. Her route to the quarterfinals has not been without struggles, featuring a come-from-behind three-set triumph over ninth seed Elena Rybakina. Vondrousova's game is built on craft, variety, and an unorthodox style that can also unsettle even the most powerful players. Unseeded, a former Grand Slam winner, her recent surprise over Rybakina, a former Wimbledon champion in her own right, is evidence that she has the mental and physical strength to compete against the biggest names.

The head-to-head contest between Aryna Sabalenka and Marketa Vondrousova is a closely contested one. Their head-to-head competition has been ebbing and flowing for almost ten years, with Sabalenka leading by a slim 5-4 advantage.

Their recent meetings this year have been particularly insightful. Vondrousova defeated Sabalenka in Berlin, but Sabalenka got revenge in Cincinnati with a three-set victory. Their only previous Grand Slam meeting was at the 2022 Australian Open, which Sabalenka won in three sets.

The tactical battle will be a classic battle of strength versus art. Sabalenka will rely on her massive power, aggressive serve, and hitting groundstrokes to overpower Vondrousova. She will attempt to hit through the court and keep the rallies short, as she has the most potent weapon in her arsenal in her power.

To her right side, Ondrousova slices finesse shots in her attempts to throw Sabalenka off her rhythm. Ondrousova will slice, vary, and use drop shots to both fully exploit and add to Sabalenka’s challenges. Her ability to alter the pace of the game and her southpaw serve will be crucial in pulling Sabalenka into making unnecessary mistakes. This will be a defensive test of Vondrousova against Sabalenka's relentless offense.

The odds-on wagering for these two thrilling encounters are up at Stake.com. Iga Swiatek is the heavy favorite against Amanda Anisimova, reflecting her dominant form in the majors this year. The odds for an Anisimova victory are considerably longer, but her recent Wimbledon final appearance reveals she is more than capable of springing a surprise. In the second encounter, Aryna Sabalenka is the heavy favorite against Marketa Vondrousova. But the odds for victory for Vondrousova are tighter than you'd have expected for an unseeded opponent facing world No. 1, reflecting her great form in recent times and her ability to beat Sabalenka.

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While Amanda Anisimova's current run and confidence on hard courts are all the more impressive, it is difficult to overlook Iga Swiatek's dominance and consistency at the majors this year. Swiatek has been dominating the tournament and is the queen of playing under pressure. Anisimova will certainly be able to mount a much more serious challenge than she was at Wimbledon, but Swiatek's strategic edge and all-court play should be enough to take a close-fought match.

• Final Score Prediction: Iga Swiatek wins 2-0 (7-5, 6-3)

This is a classic mismatch of styles and a difficult one to call. Sabalenka's raw strength and big serve are a clear plus for her on hard surfaces, but Vondrousova's intelligent tennis and recent victory over Sabalenka remind us that she has what it takes to cause upset. We are expecting a thrilling, three-set battle, with the two players taking turns pushing the other to the limits. But Sabalenka's current confidence and determination to win her first US Open title must take her over the line.

• Final Score Prediction: Aryna Sabalenka beats 2-1 (6-4, 4-6, 6-2)

The winners of these two quarter-final matches will not only qualify for the semi-finals but also position themselves as the flat favorites to lift the title. The world is in for a day of top-class tennis that will have seismic implications for the remaining stages of the tournament and the pages of history.